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Skin Cells Bypass Stem-Cell Phase to Transform Into Nerve Cells
A UW-Madison research group has converted skin cells from people and monkeys into a cell that can form a wide variety of nervous-system cells - without passing through the do-it-all stage called the induced pluripotent stem cell, or iPSC.
Bypassing the ultraflexible iPSC stage was a key advantage, says senior author Su-Chun Zhang, a professor of neuroscience and neurology. "IPSC cells can generate any cell type, which could be a problem for cell-based therapy to repair damage due to disease or injury in the nervous system."
In particular, the absence of iPSC cells rules out the formation of tumors by pluripotent cells in the recipient, a major concern involving stem cell therapy.
A second advance comes from the virus that delivers genes to reprogram the adult skin cells into a different and more flexible form. Unlike other viruses used for this process, the Sendai virus does not become part of the cell's genes.
View more UWSMPH news | SMPH Update (May 2013) | Submit your news
Call for Applications: 2013 Lily's Fund Grace Grants
The University of Wisconsin School of Medicine and Public Health, through the Office of the Senior Associate Dean for Basic Research, Biotechnology and Graduate Studies, announces a call for applications for the 2013 Lily’s Fund Grace Grants.
The Lily’s Fund Grace Grants will provide financial support for projects in epilepsy related research. Grace Grants applications should propose innovative research that, if successful, will enrich our understanding of epilepsy, advance new epilepsy treatments, identify new diagnostic tools, or otherwise improve quality of life for those who live with epilepsy.
A priority will be given to new projects that spark new thinking and open new avenues of inquiry into the mechanisms of epilepsy.
Applications may be submitted by any UW-Madison faculty or academic staff member(s) who have the skills, knowledge, and resources necessary to carry out meaningful epilepsy-related research.
The Lily’s Fund Grace Grants provide up to $100,000 ($50,000 per year) over two years. No indirect costs may be charged to this award.
Save the Date: Simulation Days, June 5-7
Mark your calendar for “Simulation Days,” June 5-7, to celebrate the accomplishments of the UW Health Clinical Simulation Program since opening in November 2011.
Activities include daily simulation demonstrations, demonstration of "Sim Wars" by emergency medicine, a free course for UW Health employees and a demonstration of the new Central Lines Insertion Training Simulator. There will also be a "Name the Manikins" contest.
More Upcoming Events
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